ODCs

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4 associated genes
No signs/symptoms info

COMMON GENES: 1
PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
12 signs/symptoms

Hereditary persistence of fetal hemoglobin - sickle cell disease

Beta-thalassemia intermedia


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	HBG2	(0.52)	HBB

Citations in the biomedical literature:

Hereditary persistence of fetal hemoglobin - sickle cell disease		Beta-thalassemia intermedia
	Synonym(s): - HPFH - sickle cell disease		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare genetic disease - Rare hematologic disease		Classification (Orphanet): - Rare genetic disease - Rare hematologic disease - Rare renal disease

	Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: - Type of inheritance: autosomal recessive

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Beta-thalassemia intermedia
	Very frequent - Anaemia - Anomalies of bones / skeletal anomalies - Hemoglobinosis / hemoglobinopathy - Microcytic anemia - Splenomegaly Frequent - Biliary / gallbladder stones / lithiasis / cholecystitis - Hepatomegaly / liver enlargement (excluding storage disease) - Hyperferritinemia / iron overload Occasional - Chronic skin infection / ulcerations / ulcers / cancrum - Hepatic / liver neoplasm / tumor / carcinoma / cancer - Pulmonary hypertension - Venous thrombosis / phlebitis / thrombophlebitis
Hereditary persistence of fetal hemoglobin - sickle cell disease
(no data available)